Platelet-rich plasma loaded nerve guidance conduit as implantable biocompatible materials for recurrent laryngeal nerve regeneration

Abstract Vocal cord paralysis caused by recurrent laryngeal nerve (RLN) injury during thyroidectomy results in hoarseness, aspiration, and dyspnea.We evaluated the usefulness of nerve guidance conduits (NGCs) constructed from an asymmetric polycaprolactone (PCL)/Pluronic F127 porous membrane and filled with platelet-rich plasma (PRP) for functional

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Description of Bothriurus mistral n. sp., the highest-dwelling Bothriurus from the western Andes (Scorpiones, Bothriuridae), using multiple morphometric approaches.

We describe Bothriurus mistral n.sp.(Scorpiones, Bothriuridae) from the Chilean igora vibrance 6-16 north-central Andes of the Coquimbo Region.This is the highest elevational discovery for Bothriurus in the western slopes of the Andes.This species was collected in the Estero Derecho Private Protected Area and Natural Sanctuary as part of the First

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Evaluation of Continuous Lactate Monitoring Systems within a Heparinized In Vivo Porcine Model Intravenously and Subcutaneously

We present an animal model used to evaluate the in vivo performance of electrochemical amperometric continuous lactate sensors compared to blood gas instruments.Electrochemical lactate sensors were fabricated, placed into 5 Fr central venous catheters (CVCs), and paired with crown apple costume wireless potentiostat devices.Following in vivo evalua

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Spatial Distribution and Predictive Significance of Dendritic Cells and Macrophages in Esophageal Cancer Treated With Combined Chemoradiotherapy and PD-1 Blockade

BackgroundThe first clinical study (NCT03671265) of first-line chemoradiotherapy combined with PD-1 blockade showed promising treatment outcomes in ashley furniture porter b697-92 (porter 3-drawer nightstand) locally advanced esophageal squamous cell carcinoma (ESCC).However, partial patients did not respond to the combination treatment.The roles o

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